Hippocampal High-Frequency Stimulation Inhibites the Progression of Rapid Kindling-Induced Seizure in Rats
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چکیده
منابع مشابه
Increasing the Effectiveness of Carbamazepine by Low Frequency Electrical Stimulation During CA1 Hippocampal Kindling on Seizure Scales in Adult Male Rats: An Experimental Study
Background and Objectives Nowadays, the application of Low Frequency Stimulations (LFS) has been considered as an alternative treatment in drug-resistant epileptic patients. So, the aim of this study was to determine the co-administration effects of LFS and carbamazepine (CBZ) during epileptogenesis in dorsal hippocampus using electrical Kindling method on seizure scales in adult male rats. ...
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15 صفحه اولAssessment of the Optimal Stimulus Pattern to Achieve Rapid Dorsal Hippocampal Kindling in Rats
Introduction: Although hippocampus is the most famous brain area involved in temporal lobe epilepsy, hippocampal kindling (HK) develops very slowly. Hence, rapid kindling is usually preferred to the traditional kindling and it is widely used. In this article we aimed at finding the optimal stimulus pattern, which yields the fastest HK rate. Methods: Stimulus patterns with different duratio...
متن کاملEffect of an ectonucleotidase inhibitor on anticonvulsant actions of low-frequency electrical stimulation in perforant path rapid kindling in rats
Introduction: Considering high prevalence of epileptic disease and considering that 40 percent of epileptic patients are resistant to drug therapy, it needs more researches to find new therapeutic ways. LFS is among the new methods for epilepsy treatments. One possible mechanism involved in the anticonvulsant effect of LFS is increased adenosine. Therefore, in this study the role of adenosin...
متن کاملThe Effect of Sodium Valproate and Low Frequency Electrical Stimulation on Motor Activity During Rapid Kindling of Hippocampal CA1 Region in Adult Male Rat: An Experimental Study
Background and Objectives: Epilepsy is a chronic neurological disorder that requires long treatment with less side effects. Therefore, this study aimed to determine the effect of sodium valproate and electrical stimulation of the brain with low frequency (LFS) on the motor activity of male rat during hippocampus rapid kindling. Material and Methods: In this experimental study, 56 male adult ra...
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ژورنال
عنوان ژورنال: Neuroscience and Medicine
سال: 2013
ISSN: 2158-2912,2158-2947
DOI: 10.4236/nm.2013.42011